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  • Genetics: A Conceptual Approach, 5th Edition

    NOTE: Access Code is NOT INCLUDEDWith Genetics: A Conceptual Approach, Ben Pierce brings a master teacher’s experiences to the introductory genetics textbook, clarifying this complex subject by focusing on the big picture of genetics concepts and how those concepts connect to one another.   The new edition features Pierce's signature writing style, relevant applications, student-friendly art, and emphasis on problem-solving, while incorporating the latest trends in genetics research. The new edition text and LaunchPad media work closely together for a seamless experience for both instructors and students.

    • ASIN: 146410946X
    • Brand: Brand: W. H. Freeman
    • ASIN: 146410946X

  • 88849 - Pierce Protein L Magnetic Beads, Thermo Scientific - Protein L Magnetic Beads - Each (1ml)

    Thermo Scientific Protein L Magnetic Beads are high-capacity and high-throughput affinity particles for antibody purification using manual or robotic magnetic separators. Immobilized Protein L is Ideal for Selective Purification of Human and Mouse Antibodies that have kappa Light Chains Low Non-Specific Binding of Stable, Pre-Blocked Beads Provide Clean Purification of Antibody Beads are Compatible with Manual and Automated Workflows Making it VersatileRecombinant Protein L, covalently attached to a blocked magnetic bead surface, selectively binds mouse and human antibodies through kappa light chains Thermo Scientific Protein L Magnetic Beads are typically used for purifying mouse and human antibodies containing kappa light chains from serum, cell culture supernatant or ascites. Protein L can bind a broader range of Ig classes than Protein A or Protein G, including IgG, IgM, IgA, IgE and IgD. Protein L binds strongly to human (kappa I, III and IV only), mouse (kappa I only), rat and pig immunoglobulins. It binds weakly to rabbit immunoglobulins and does not bind bovine, goat or sheep immunoglobulins. Single chain variable fragments (scFv) and Fab fragments also bind to Protein L. The protocol for the Protein L beads has been optimized to allow for high recovery and high purity of...

    • ASIN: B07M7G7QH9
    • Brand: Thermo Scientific
    • ASIN: B07M7G7QH9
    • Part No: 88849

  • 16107 - Pierceâ" GST Spin Purification Kit, Sufficient for Purifying ~10 mg of GST-Tagged Protein per Column - Pierce Glutathione Spin Columns, Thermo Scientific - Each

    This Thermo Scientific Pierce GST Spin Purification Kit contains Pierce Glutathione Spin Columns and buffer components to provide a fast, easy-to-use format for purifying GST-fusion proteins from cellular lysates. -Glutathione is immobilised through its central sulfhydryl onto 6% crosslinked agarose resin -High capacity binds at least 40 mg of purified recombinant GST protein per milliliter of resin -Consistently purifies at least 10 mg of GST-tagged protein per milliliter of resin with greater than 90% purity -Resin can be reused at least five times without reduction in performance For Research Use Only. Not for use in diagnostic procedures. Delivery information:Kit includes Pierceâ" Glutathione spin columns, Equilibration/Wash Buffer, 125 mM Tris, Glutathione, and column plugs. The 0.2 mL kit also includes collection tubes.

    • ASIN: B07FMD1234
    • Brand: Thermo Scientific
    • ASIN: B07FMD1234
    • Part No: 16107

  • Protein Kinase C: Emerging Roles and Therapeutic Potential (Biochemistry Research Trends)

    In this compilation, the authors review the structural basis of PKC isozymes and focus on the C1 domain, as well as the plausible binding mechanisms of its activators. Additionally, the recent molecular dynamics simulation studies of how phorbol esters or bryostatin bind to the activator pocket are described and some of the key amino acid residues recently identified as important for activator binding are investigated. The following chapter focuses on the expression pattern and function of PKC in cancer cells, and newly emerging PKC -targeted cancer therapies. PKC acts directly and/or indirectly in various signaling mechanisms in cancer cells, including proliferation, survival, invasion, migration, apoptosis and drug resistance. A final review is provided which dissects the crosstalk between p53 and PKC in the context of apoptotic cell death and cancer therapy. PKC is implicated in a transcriptional regulation of the p53 tumor suppressor that is critical for cell cycle arrest and apoptosis in response to DNA damage.

    • ASIN: 1536132101
    • ASIN: 1536132101

  • Vascular Biochemistry (Developments in Molecular and Cellular Biochemistry Book 41)

    This volume explores all aspects of vascular biochemistry and includes chapters that provide an understanding of vascular function with descriptions of tissue components present in the vascular wall as well as an exploration of the hemodynamic and metabolic activities associated with this function. In addition, some chapters explore the vasculature under conditions which mimic various disease states. The information provided in this volume will provide new insights into the mechanisms that control vascular function as well as therapies designed to treat vascular disease.

    • ASIN: B0013KXFKS
    • ASIN: B0013KXFKS

  • 77679 - Pierce Recombinant Protein L, Thermo Scientific - Size : 50 mg - Each (50mg)

    Purified (unconjugated) Thermo Scientific Pierce Recombinant Protein L is useful as the basis for preparing various kinds of probes or affinity media for detection or purification of mouse and human antibodies in immunoassays and antibody purification protocols. Contains four immunoglobulin-binding domains per protein Binds members of all classes of Ig (IgG, IgM, IgA, IgE and IgD) that contain kappa light chains Binds single chain variable fragments (scFv) and Fab fragments that contain kappa light chainsProtein L is an immunoglobulin-binding protein that was originally derived from the bacteria Peptostreptococcus magnus, but is now produced recombinantly. Protein L has the unique ability to bind through kappa light chain interactions without interfering with an antibody's antigen-binding site. This gives Protein L the ability to bind a wider range of Ig classes and subclasses than other antibody-binding proteins. Protein L will bind to all classes of Ig (IgG, IgM, IgA, IgE and IgD). Protein L will also bind single chain variable fragments (scFv) and Fab fragments. Protein L binds kappa I, III, and IV in human and kappa I on mouse. Form: salt-free powderA280 of 0.1% solution: 0.80Isoelectric point (pI): 4.8

    • ASIN: B07MC62Q1K
    • Brand: Thermo Scientific
    • ASIN: B07MC62Q1K
    • Part No: 77679

  • 16108 - Pierceâ" GST Spin Purification Kit, Sufficient for Purifying ~30 mg of GST-Tagged Protein per Column - Pierce Glutathione Spin Columns, Thermo Scientific - Each

    This Thermo Scientific Pierce GST Spin Purification Kit contains Pierce Glutathione Spin Columns and buffer components to provide a fast, easy-to-use format for purifying GST-fusion proteins from cellular lysates. -Glutathione is immobilised through its central sulfhydryl onto 6% crosslinked agarose resin -High capacity binds at least 40 mg of purified recombinant GST protein per milliliter of resin -Consistently purifies at least 10 mg of GST-tagged protein per milliliter of resin with greater than 90% purity -Resin can be reused at least five times without reduction in performance For Research Use Only. Not for use in diagnostic procedures. Delivery information:Kit includes Pierceâ" Glutathione spin columns, Equilibration/Wash Buffer, 125 mM Tris, Glutathione, and column plugs. The 0.2 mL kit also includes collection tubes.

    • ASIN: B07FM9F44W
    • Brand: Thermo Scientific
    • ASIN: B07FM9F44W
    • Part No: 16108

  • 88533 - Pierce Protein Concentrators PES Thermo Scientific - Pierce Protein Concentrator PES - Pack of 24 (20ml)

    Protein Concentrators PES are disposable ultrafiltration centrifugal devices with a polyethersulfone (PES) membrane for concentration, desalting, and buffer exchange of biological samples. Molecular weight cutoff Can be used for processing sample volumes Rapid protein concentration Excellent protein recovery Versatile sample concentrations, diafiltrations, or buffer-exchange of biological samples Reliable, consistent resultsPierce Protein Concentrators PES are disposable ultrafiltration centrifugal devices with a polyethersulfone (PES) membrane for concentration, desalting, and buffer exchange of biological samples. This product has a molecular weight cutoff (MWCO) and can be used for processing various sample volumes. Protein Concentrators may be used in both fixed angle and swing bucker rotors; collect and recover sample without invert spinning. For easy identification, the MWCO value is etched on the side of each device. To assist with sample addition and recovery, a clear window with graduations is located on the side of each device enabling visual determination of the retentate volume. The vertical design of the membrane allows high flux rates, low nonspecific binding, and negligible protein aggregation on the membrane; and it offers reliable and consistent results. Pierce P...

    • ASIN: B0732FST5Q
    • Brand: Thermo Scientific
    • ASIN: B0732FST5Q
    • Part No: 88533

  • CAMPFY Stainless Steel Boba Straw Original Set: 5 Angled-Tip Straws & Cleaning Brush - Wide Bubble Tea Straws - Reusable Metal Drinking Straws for Reduced Plastic Consumption - Dishwasher Safe

    Don't become a culprit.Americans use an average of 1.6 straws per day. This cumulatively amounts to 390 million plastic straws used and disposed while they contribute to the 8 million metric tons of total plastic waste dumped into the oceans annually. At this rate, by 2050, there will be more plastic in the ocean than fish. Since it takes at least 200 years before plastic straws decompose, they tend break down into smaller and smaller pieces that are soon ingested by marine life. Moreover, according to a recent study, by 2050, 99% of all seabirds will have ingested plastic.However, some people still need straws. They provide easier access to our beverages that are especially crucial for people with disabilities and those concerned with hygiene.CAMPFY Stainless Steel Straws can offer a compromise. You never have to worry about your plastic consumption while enjoying your drink!CAMPFY Stainless Steel Straws will help you reduce your plastic consumption by opting out from those pesky straws that pollute our oceans. These reusable FDA approved food-grade stainless steel straws do not contain any artificial dyes, colors, or finishing chemicals that might harm your health.Easily travel with these earth-cancious straws with its reusable travel bag and cleaning brush for portable and eas...

    • ASIN: B07J1XJ45N
    • Color: Original
    • Brand: CAMPFY
    • ASIN: B07J1XJ45N

  • 88529 - Pierce Protein Concentrators PES Thermo Scientific - Pierce Protein Concentrator PES - Pack of 10 (20ml)

    Protein Concentrators PES are disposable ultrafiltration centrifugal devices with a polyethersulfone (PES) membrane for concentration, desalting, and buffer exchange of biological samples. Molecular weight cutoff Can be used for processing sample volumes Rapid protein concentration Excellent protein recovery Versatile sample concentrations, diafiltrations, or buffer-exchange of biological samples Reliable, consistent resultsPierce Protein Concentrators PES are disposable ultrafiltration centrifugal devices with a polyethersulfone (PES) membrane for concentration, desalting, and buffer exchange of biological samples. This product has a molecular weight cutoff (MWCO) and can be used for processing various sample volumes. Protein Concentrators may be used in both fixed angle and swing bucker rotors; collect and recover sample without invert spinning. For easy identification, the MWCO value is etched on the side of each device. To assist with sample addition and recovery, a clear window with graduations is located on the side of each device enabling visual determination of the retentate volume. The vertical design of the membrane allows high flux rates, low nonspecific binding, and negligible protein aggregation on the membrane; and it offers reliable and consistent results. Pierce P...

    • ASIN: B0732JPPPF
    • Brand: Thermo Scientific
    • ASIN: B0732JPPPF
    • Part No: 88529