Thermo Scientific Protein L Magnetic Beads are high-capacity and high-throughput affinity particles for antibody purification using manual or robotic magnetic separators. Immobilized Protein L is Ideal for Selective Purification of Human and Mouse Antibodies that have kappa Light Chains Low Non-Specific Binding of Stable, Pre-Blocked Beads Provide Clean Purification of Antibody Beads are Compatible with Manual and Automated Workflows Making it VersatileRecombinant Protein L, covalently attached to a blocked magnetic bead surface, selectively binds mouse and human antibodies through kappa light chains Thermo Scientific Protein L Magnetic Beads are typically used for purifying mouse and human antibodies containing kappa light chains from serum, cell culture supernatant or ascites. Protein L can bind a broader range of Ig classes than Protein A or Protein G, including IgG, IgM, IgA, IgE and IgD. Protein L binds strongly to human (kappa I, III and IV only), mouse (kappa I only), rat and pig immunoglobulins. It binds weakly to rabbit immunoglobulins and does not bind bovine, goat or sheep immunoglobulins. Single chain variable fragments (scFv) and Fab fragments also bind to Protein L. The protocol for the Protein L beads has been optimized to allow for high recovery and high purity of...
- ASIN: B07M7G7QH9
- Brand: Thermo Scientific
- ASIN: B07M7G7QH9Part No: 88849